Running straight through pipes

I finished jetting my 80 kz250d with pods for future reference 135 jet and my muffler decided it would like to rust off where the PO welded it so that pipe is gone. I found a slash cut harley muffler I received as partial payment for a computer fix and welded that on. the bike stock had 98 2nd main 68 primary and upjetted to 135 2nd main 72 main jets. the bike is fine crusing but now with this pipe no top end would I need an ever larger 2nd main to compenste for this pipe? If so anyone have a guess how much of a jump/

If you had open pipes, and now have a muffler, and you Jetted for the open pipes, then you should be to rich now. You have created back pressure, and the engine will need less Jet on the top end/ main jet.