CR 26 Help

Hey all, it's been a while since i've last posted on here but i've been working on my '81 GPz after my mishap with my engine bending some valves. A used engine later and custom spigots for my CR26 carbs later (due to '81's having smaller intakes than later years), i am now running into jetting issues, obviously. I guess my question is what should i touch when re-jetting these carbs? Since they are for later GPz heads, should i go down a size or two with everything? (mains, pilot, starter, needle) What i have already is 105 mains, 220 air, 65 starter from what sudco has told me. I mean, it won't even start without fouling the plugs. Any advice will help, jetting is a science that always seems to be a mystery to me lol